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Heart 1998;79:548-553 ( June )
Department of Cardiology, The Regional Cardiothoracic
Centre, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK
Correspondence to: Dr Gribbin, c/o Dr McComb's Secretary.
Accepted for publication 3 February 1998
Objective
To assess the natural history of
the atrial rhythm of patients with paroxysmal atrial arrhythmias
undergoing atrioventricular node ablation and permanent pacemaker implantation.
Design and setting
A retrospective cohort
study of consecutive patients identified from the pacemaker database
and electrophysiology records of a tertiary referral hospital.
Patients
62 consecutive patients with
paroxysmal atrial arrhythmias undergoing atrioventricular node ablation
and permanent pacemaker implantation between 1988 and July 1996.
Main outcome measures
(1) Atrial rhythm on final
follow up ECG, classified as either ordered (sinus rhythm or atrial
pacing) or disordered (atrial fibrillation, atrial flutter or atrial
tachycardia). (2) Chronic atrial fibrillation, defined as a disordered
rhythm on two consecutive ECGs (or throughout a 24 hour Holter
recording) with no ordered rhythm subsequently documented.
Results
Survival analysis showed that 75% of
patients progressed to chronic atrial fibrillation by 2584 days (86 months). On multiple logistic regression analysis a history of
electrical cardioversion, increasing patient age, and VVI pacing were
associated with the development of chronic atrial fibrillation. A
history of electrical cardioversion and increasing patient age were
associated with a disordered atrial rhythm on the final follow up ECG.
Conclusions
Patients with paroxysmal atrial
arrhythmias are at high risk of developing chronic atrial fibrillation.
A history of direct current cardioversion, increasing patient age at
the time of ablation, and VVI pacing are predictive of the development
of chronic atrial fibrillation in this patient group.
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